Toxicity of pneumolysin to pulmonary endothelial cells in vitro
نویسندگان
چکیده
منابع مشابه
Pneumolysin activates phospholipase A in pulmonary artery endothelial cells.
Pneumolysin has been identified as a virulence factor in Streptococcus pneumoniae disease. In addition to producing tissue injury through its cytolytic effect, pneumolysin might injure tissues indirectly by eliciting an inflammatory response. We demonstrate for the first time that pneumolysin is a rapid and potent activator of cellular phospholipase A in bovine pulmonary artery endothelial cell...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 1992
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.60.5.1740-1746.1992